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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
11.82
Human Site:
S276
Identified Species:
21.67
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S276
N
T
L
Q
T
L
T
S
Q
L
L
K
R
D
P
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
S276
N
T
L
Q
T
L
T
S
Q
L
L
K
R
D
P
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
N276
N
T
L
Q
T
L
T
N
Q
L
L
K
R
D
P
Dog
Lupus familis
XP_848489
830
94828
N278
N
T
L
Q
N
L
T
N
Q
L
L
K
R
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
N268
N
T
L
Q
T
L
T
N
Q
L
L
K
R
D
P
Rat
Rattus norvegicus
NP_001012157
828
94228
N276
N
T
L
Q
T
L
T
N
Q
L
L
K
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
S273
N
T
L
Q
N
L
T
S
Q
L
M
K
R
D
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
G275
N
T
L
Q
N
L
T
G
Q
L
S
K
R
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
E263
S
V
I
N
Q
A
T
E
A
T
L
H
P
K
N
Honey Bee
Apis mellifera
XP_393867
799
92557
D247
E
S
I
L
N
L
K
D
N
D
D
S
Q
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
Q263
A
L
M
E
Q
V
E
Q
R
L
D
K
T
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
S262
A
V
L
K
T
A
A
S
Q
V
Q
A
A
F
R
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
T253
L
T
G
L
P
S
T
T
R
D
A
F
L
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
80
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
N.A.
80
N.A.
26.6
33.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
16
8
0
8
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
16
16
0
0
70
0
% D
% Glu:
8
0
0
8
0
0
8
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
0
70
0
8
0
% K
% Leu:
8
8
70
16
0
70
0
0
0
70
54
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
62
0
0
8
31
0
0
31
8
0
0
0
0
0
16
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
62
% P
% Gln:
0
0
0
62
16
0
0
8
70
0
8
0
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
16
0
0
0
62
0
8
% R
% Ser:
8
8
0
0
0
8
0
31
0
0
8
8
0
8
8
% S
% Thr:
0
70
0
0
47
0
77
8
0
8
0
0
8
0
0
% T
% Val:
0
16
0
0
0
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _